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OFFICE OF TECHNOLOGY MANAGEMENT

AVAILABLE TECHNOLOGIES

While You are Browsing Invention Databases, Your Competition May Have Already Licensed the UCSF Technology You Need.

The best way to access UCSF technologies is to provide the Office of Technology Management (by e-mail to the Director) with a list of your company's technology needs and the name and e-mail address of your company representative(s). This information is shared with all Licensing Officers and if one of them already has or encounters a technology in the future that meets your specifications, that individual will contact your representative directly. Please provide as much detail as possible and keep your technology list and company representative contact information current (i.e. please specify if your preferred drug is a protein, small molecule, antisense, RNAi, etc. so we do not alert you about a technology you cannot use).

Although we do occasionally post UCSF inventions in the following database, it is by no means comprehensive or representative because our best and newest inventions often get licensed before they get posted.

Selected Technologies Available from the UCSF Office of Technology Management

#SF1992-A70 Gene Therapy by Small Fragment Homologous Replacement
Kaposi's Syndrome Herpesvirus Protease and Assembly Protein
#SF1997-037 Transcription Factor for Control of Cardiac Gene Expression

#SF1997-059 Eukaryotic High Rate Mutagenesis System
#SF1997-063, 064 Methods for Detecting and Screening Drug Candidates Against Kaposi's Sarcoma-Associated Herpesvirus
#SF1997-089 New Fas Ligand with Improved Therapeutic Potential
#SF1997-090-2 Non-invasive Imaging Method for Grading Tumors
#SF1997-092

Simultaneous Determination of Blood Groups and Serum Antibodies by Flow Cytometry

#SF1997-093 Blind Separation of Mixed Signals from Convolved Sources
#SF1997-095 Improved Nasal Fixation System
#SF1997-134 Family of Small Molecule Compounds that Inhibit both HIV Reverse Transcriptase and Integrase
#SF1997-138 Methods for the Treatment of Post-operative Ileus

#SF1997-145,
#SF2000-067

Novel Compounds for Treatment of Parasitic Protozoa
#SF1997-151, 160 Novel Candida albicans Virulence Genes
#SF1997-154

Murine Model for Studying Megakaryocyte Genetics

#SF1997-159

New Family of Amino Acid Neurotransmitter Transporters

#SF1998-010,
#SF1999-070
Intellectual Property Portfolio for Investigation of Therapies for Type 1 Diabetes
#SF1998-026 Modulation of B-cell Chemoattractant/Receptor Interaction as Treatment for Immune Disease
#SF1998-087

Method for Nucleic Acid Structure-based Virtual Drug Discovery

#SF1998-108 Method for Reducing Surfactant Inactivation in Pulmonary Surfactant Therapy
#SF1999-003

High Affinity Inhibitors of SH3 Domain-mediated Protein-protein Interactions

#SF1999-024

Vaccuum Actuated Surgical Retractors

#SF1999-038 Pseudomonas aeruginosa Vaccine
#SF1999-048

Target for Enhancement of the Antitumor Activity of Angiogenesis Inhibitors

#SF1999-062 Novel Genes in the JNK Signaling Pathway
#SF1999-063 Novel Cell Line for Studying Drug Transport and Delivery with Regulated Gene Expression
#SF1999-065 Determination of Protein Fold Recognition Using Chemical Cross-linking and Mass Spectrometry
#SF1999-067

Parathyroid Hormone Analogues Useful for Treatment of Osteoporosis

#SF1999-077

A Visual Technique for Radioguided Surgery

#SF1999-085

Detection of DNA Repair Defects in Infertile Men

#SF1999-089 Use of Streptococcus thermophilus lacZ as a Versatile Reporter Gene for Candida albicans
#SF1999-093

Delivery of Gene Therapy to Cornea or Skin

#SF1999-095

A Successful Genetic Targeting Sequence for Use in Proliferative Disease Therapy

#SF1999-101

Novel Calcium Transporting ATPase in Keratinocytes

#SF2000-002, #SF2003-041, #SF2003-078, #SF2004-041 Intellectual Property Portfolio for Treatment and Management of Pain
#SF2000-006

Regulation of the Solubility and Subcellular Localization of Polyglutamine Proteins

#SF2000-044 A Mouse Model for Autoimmune Lupus Glomerulonephritis
#SF2000-047 Targeted Cytotoxic Gene Therapy for Human Papillomavirus Infection
#SF2000-057,
#SF2001-012,
#SF2001-073
Human Prostatic Epithelial Cell Lines
#SF2000-074 & #SF1998-005 Compositions and Methods for Identifying Agents that Modulate IGE Production and Mast Cell Degranulation
#SF2001-040 A New Mouse Model for the Study of Obesity
#SF2001-059 A Device for Sutureless Vascular Anastomosis
#SF2001-071 #SF2004-054 Novel Small Molecules for the Treatment of Parasitic Diseases: Trichomoniasis, Malaria, Chagas Disease
#SF2001-078 Improved Gene Transfer and Wound Healing
#SF2001-082 A More Effective Chest Tube Using the Seldinger Technique
#SF2001-099 A Multiplexed In Vivo Assay of Small Molecule Structure Space
#SF2001-101 Method to Improve Efficacy of Adenoviral Vectors for Gene Therapy
#SF2002-008 A novel Candida albicans library
#SF2002-031 A Novel Prosthesis Extractor for Shoulder Implants
#SF2002-035 Novel Macromolecular Contrast Agents and Pathways for Synthesis
#SF2002-041 DoseTailor: A Dosing Parameters Software Package for Antineoplastics
#SF2002-079 Recombinant Human Protein that Promotes Neurite Growth In vitro
#SF2002-092 Automated Technical and Professional Fee Billing Program
#SF2003-011 A Home/Office Self-Screening Oral Cancer Kit
#SF2003-012 & #SF2003-038 Proteome-wide Phosphopeptide Mapping by Site-Specific Proteolysis
#SF2003-013 Precision MEMS micro-cutting device for cellular microsurgery
#SF2003-017 Diaryl Urea Compounds as Anticancer Agents via Inhibition of the IGF-IR
#SF2003-030 A Method to Regulate Tooth Movement and Sutural Expansion in Orthodontics
#SF2003-049 A New Method for Producing Large Quantities of Proliferating Myocytes for Transplantation
#SF2003-052 Novel potential therapeutic targets to treat inflammation
#SF2003-057 Novel Selective Inhibitors of p90 ribosomal S6 kinases: RSK1 and RSK2
#SF2003-069 A Transgenic Mouse for Rapid and Sensitive In Vivo Tumor Detection and Evaluation
#SF2003-101 Novel 3D Wavelet-Based Filter for Visualizing Features in Noisy Biological Data
#SF2004-004 Novel indications for transforming growth factor beta modulating agents (agonists and antagonists)
#SF2004-017

NOVEL THERAPY FOR TREATMENT OF CHRONIC DEGENERATIVE BRAIN DISEASES

#SF2004-021 Novel Methodologies For Vaccine Development
#SF2004-031 Spin-lock magnetic resonance angiographic and perfusion imaging method
#SF2004-051 Software to Predict Clinical Benefit of Pacemaker Placement through Ventricular Synchrony Assessment
#SF2004-068 Mechanism based cross-linkers for identifying kinase-substrate interactions
#SF2004-073 New Human Parvovirus
#SF2004-076 Rapid and Sensitive Method for Determining Sex of Pre-implantation Embryo
#SF2004-084 Cell Line Producing Fc Control Protein (Fc Portion of Human IgG)
#SF2004-097

New Method for Tissue Selective Gene or Virus Expression

#SF2004-099 Inclinometers For Radiographic Imaging
#SF2004-100 Mouse Model for Studying Epithelial Derived Tumors
#SF2004-A37 Treatment for Pulmonary Edema, Acute Lung Injury, and Vascular Permeability
#SF2004-A39 Internalizing Human Monoclonal Antibodies for Prostate Cancer
#SF2005-004 Novel Drug Discovery Targets to Improve Human Aging
#SF2005-005 Carcinogenesis Model Encompassing the Range of Prostate Cancer Progression and Metastasis
#SF2005-022 Ilios: An Award-Winning Medical School Curriculum Management Tool
#SF2005-025

Natural Skin Penetration Enhancement System

#SF2005-036 Facial and Ocular Muscle Modulation Using Electrochemical Implants
#SF2005-045 Experimental model of smoke-induced lung cancer
#SF2005-046 Photochemical inhibition of ionotropic glutamate receptors
#SF2005-050 Strains and plasmids for making homozygous knockouts in C. albicans
#SF2005-065 RNAi-Based Anti-Inflammatory Treatment for Irritable Bowel Syndrome
#SF2005-066 saRNA-directed Transcriptional Activation
#SF2005-076 A novel device for isolating colonies of adherent cells in vitro
#SF2005-077 Physiologically Relevant Mouse Models of Breast Cancer
#SF2005-078 Cell Line Useful for Studying the Effects of UV Damage on DNA Repair
#SF2005-084 A Method for Prevention of Gallstones
#SF2005-087 Medical Device to Treat Inflammatory Airway Diseases Such As Asthma
#SF2005-080 A Method To Inhibit Cancer Growth By Preventing The Interaction Between Fbxw8 And Cyclin D1
#SF2005-088 High Throughput Bioassay for Modulators of cAMP Cyclase and cAMP Kinase Activity
#SF2005-091 Resolution Enhancement of MRI and Medical Spectroscopic/Imaging Methods
#SF2005-092 Improving Difficult Airway Management: A New Cricothyrotomy Tool
#SF2005-096 Mouse Model of Hepatocellular Carcinoma
#SF2005-101 Improved Surgical Site Radiographic Markers and Delivery Platform
#SF2005-102 Phosphoprotein-specific Monoclonal Antibody Library
#SF2005-106 A new transgenic mouse line to study adult neurogenesis
#SF2005-119 Improving Vaccines: Increased Viral Attenuation and Fidelity
#SF2005-121 A diagnostic test to personalize patient therapy using platinum-based anticancer drugs
#SF2005-123 Extracellular Modulator of Hedgehog Signaling
#SF2005-C12-1 Antibodies Specific for Bovine PrP
#SF2006-007 Novel VEGF-activated Protein
#SF2006-017 Improving the Resolution of Wide Field Microscopy
#2006-020 Cancer Vaccine using Improved Antigen-Presenting Tumor Cells
#SF2006-030 &
SF2006-096
Diagnostic and Therapeutic Targets in Melanoma Subtypes
#SF2006-034 Novel Target for Treatment of Fatty Liver Disease
#SF2006-041 Preeclampsia and Preterm Labor: Novel Targets for Prevention and Intervention
#SF2006-044 p120ctn Floxed Mouse for Generation of Conditional Knockout Mouse
#SF2006-045 Integrin ß-8 Floxed Mouse for Generation of Conditional Knockout Mouse
#SF2006-049 Percutaneous Cancer Therapeutic Drug Delivery Device
#SF2006-053 Improved method for osteoporotic fracture risk estimation
#SF2006-055 Mouse Model of Osteoporosis
#SF2006-066-112 Minimal injury dermatologic handheld laser
#SF2006-070 High Yield Production of Macrobiopolymers and Proteins in Bacteria
#SF2006-076 Novel targets associated with asthma and corticosteroid treatment
#SF2006-078 A novel multipinhole SPECT collimator design
#2006-087 A Treatment for AIDS Wasting Syndrome and Potential HIV-1 Vaccine Development
#SF2006-092 Multi-gene Diagnostic Assay for Malignant Thyroid Neoplasm and Extent of the Disease
#2006-122 Automated Computer Assessment of the Degree of Carotid Artery Stenosis
#SF2006-130 Patch clamp control system
#2007-006 Cancer Biomarkers
#SF2007-036 Positional Adjustable Glaucoma Valve Tube
#SF2007-037 High Throughput Screen for Modulators of the Unfolded Protein Response
#SF2007-061 Mouse Model of Autoimmune Polyendocrinopathy Syndrome Type I
#SF2007-065 Fully Balanced Steady State 3D-Spin-Echo Magnetic Resonance Imaging Sequence Useful for Diagnosis of Osteoporosis
#2007-071 Inverted Drill Press for Overhead Drilling
#2007-079 A Spatial Technique for Localizing Neurosurgically Implanted Electrodes
#SF2007-087 -088 -089 Mouse models Useful for Studying Infectious, Autoimmune and/or Allergic Diseases
#2007-090 Genetic manipulation of embryonic stem cells
#SF2007-095 Novel Diagnostic Biomarkers for Endometriosis
#2007-104-7 Nanostructures for Biomedical Applications
#2007-108 Novel Prenatal Diagnostic Biomarkers for Cytomegalovirus Infection
#SF2007-126 Induction of reprogramming of germ cells to pluripotent stem cells
#SF2007-136 Novel Genetic Predictors of Antidepressant Response
#SF2007-141 Methods and Tools to Reduce Biofilm Contamination in Waterlines
#SF2007-145 Novel Delivery System for Allergic Anaphylaxis
#SF2007-155 Hyperbaric Fermentation
#SF2008-017 A New Biomarker for Patient Susceptibility to Aurora Kinase Inhibitor Cancer Therapy
#SF2008-022 A Novel Activity-Based Assay For Mast Cell Chymase In Biological Fluids
#SF2008-023 Method to Protect Mammalian Cells from ER Stress
#SF2008-026 Device for Measuring Rodent Oral Function and
Evaluation of Goal Directed Behavior
#SF2008-033

Novel Method For Synthesis Of Biofuel Precursors

#SF2008-034

Novel Methods for Predicting and Treating Tumors Resistant to Drug, Immunotherapy, and Radiation

#SF2008-043

Measuring Human Gait and Movement for Diagnosis of Neurological Disease

#SF2008-047 Novel Biomarker for Autoimmune-Mediated Lung Disease
#SF2008-048 Novel Method for Erythrocyte Preservation
#SF2008-063 Increasing the Resolution of Positron Emission Tomography
#SF2008-066

A Semi-Automated, High-Throughput Rna Isolation Method From Whole Blood Samples

#SF2008-070 DCGR8 Knockout and Heterozygous Embryonic Stem Cells
#SF2008-071

Novel Biological Nanomoter for Ex-Vivo Applications

#SF2008-077

Diagnostic for Metastatic-Prone Breast Cancer
and Novel Target for Blocking Metastasis

#SF2008-081

Increasing the Efficacy of Human Umbilical Cord Stem Cell Transplantations

Highly Specific Inhibitor of Human MT-SP1

Novel Approach for Treatment of Lung Cancer

SF#2008-099 and SF2008-100 Improved Flow Cytometer Hardware Design and Software analysis Package
Device to Enable Controlled Percutaneous Ablation and Incision of Cardiovascular Structures Including Cardiac Valves
Engineered MAPK Signaling Responses

Novel Approach to Treatment of Chemo-Resistant Melanoma

New Prognostic Indicators for Hormone Receptor and Triple Negative Breast Cancers

SF #2008-132 Human Immunostimulatory T Cells
#SF2008-129 A Novel Drosophila System For Live Tissue Specific Assessment Of Drug Transport Function
#SF2008-181 New Website For Improved Access To Current Medical Guidelines

 

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